Light trapping gets a boost

Mimotope vaccine efficacy gets a "boost" from native tumor antigens

Tumor-associated antigen (TAA)-targeting mimotope peptides exert more prominent immunostimulatory functions than unmodified TAAs, with the caveat that some T-cell clones exhibit a relatively low affinity for TAAs. Combining mimotope-based vaccines with native TAAs in a prime-boost setting significantly improves antitumor immunity.

Trapping Light With Mirrors

We show that, given finitely many line-segment mirrors in the plane, that do not touch, and an arbitrary point source of light, if all angles made by lines parallel to mirrors are rational multiples of π, then all but countably many emitted light beams escape. This result is shown to imply that, for a given point source of light, a randomly chosen configuration of finitely many nontouching line...

Light Trapping with Silicon Light Funnel Arrays

Silicon light funnels are three-dimensional subwavelength structures in the shape of inverted cones with respect to the incoming illumination. Light funnel (LF) arrays can serve as efficient absorbing layers on account of their light trapping capabilities, which are associated with the presence of high-density complex Mie modes. Specifically, light funnel arrays exhibit broadband absorption enh...

Photonic crystals boost light emission

Myosin light chain phosphatase: it gets around.

The importance of Ca 2 /calmodulin-dependent myosin light chain kinase (MLCK) for smooth muscle contraction is well documented.1 Until recently, myosin light chain (MLC) phosphatase was thought to be unregulated and constitutively active. However, studies have demonstrated that smooth muscle contraction is dependent on regulation of MLC phosphatase activity.2,3 The inhibition of phosphatase act...